Neuroscience Lactic Acid Peels
- SKU:
- D8099
Neuroscience Lactic Acid Peels exfoliate without over-stressing the skin, making them gentler yet effective.
Use the dropdown menu to choose 30%, 35% or 45% Neuroscience Lactic Acid Peels. Peels.
(except Equipro, and Silhouet-Tone equipment)
The lactic peel system that works where others don't reach
Provides both exfoliation + skin support. With zero downtime.
The ClearChoice Neuroscience Lactic Peel System isn't just another lactic acid peel. It's a progressive, neurogenic peeling system designed to work with the skin's biology — not against it.
Most peels focus on the surface. This system goes below the barrier, where nerve signals are actually driving inflammation, sensitivity, and uneven healing. By modulating the skin-nervous response and vascular connection, these peels deliver enhanced results and better skin comfort without the downtime you'd expect from a professional peel.
This is beyond exfoliation. This is Agevity™-driven skin performance.
When inflammation is controlled, you get:
- Keratinocyte turnover
- Collagen signaling
- Barrier reconstruction
- Pigment normalization
Further reading
You've Been Treating the Wrong Layer →
How the system works
For years, chemical peels have been positioned around intensity. Stronger acids. Lower pH. More visible reaction. But skin doesn't improve because it's overwhelmed.
Instead of forcing rapid change through aggressive stimulation, the Neuro Signal™ system delivers structured, progressive signaling:
- Each peel builds on the last
- Each treatment prepares the skin for the next level of performance
- The result is not a temporary improvement — it's a cumulative transformation
Traditional peels rely on pH to create a reaction. Lower pH, sharper intensity, more immediate irritation. But irritation is not the goal — it's simply the skin's alarm system.
Here, neurogenic ingredients shift that response. The inflammatory cascade is moderated. The nervous system stays calm. The acid reservoir becomes structured communication — a guided biological process where exfoliation occurs without inflammation becoming the dominant signal.
Energy is no longer spent on defense. It's redirected toward regeneration, repair, and Agevity™-driven skin performance.
pH controls intensity. Percentage controls workload. Neuro-control determines the outcome.
Why we love it — and why our pros do too
- Zero downtime — neurogenic formulation supports the skin's response so results don't come at the cost of recovery
- Progressive by design — not a one-size protocol. A system that evolves with your client's skin
- Below the barrier — addresses nerve signals driving inflammation and sensitivity, not just surface symptoms
- Agevity™-driven — energy redirected from defense to regeneration, repair, and long-term skin performance
- Barrier-conscious — formulated to protect skin integrity at every step, not just exfoliate
- Modulate, not burn. Activate, not inflame. Boost results, not downtime.
Choose your strength
An advanced exfoliating system with a controlled, low-intensity signal.
Your entry point. Ideal for new clients, sensitized skin, or anyone whose barrier needs conditioning before advancing. Promotes consistent epidermal turnover with a smooth, controlled delivery profile — no unnecessary disruption, no overstimulation. This is also a great summertime peel choice.
Step 1 in the Neuro Signal™ system:
Initiates controlled turnover and prepares the skin. The skin becomes more receptive, more responsive, and better prepared for what comes next.
WHAT IT DOES
Loosens corneocyte cohesion at the surface
Begins breaking down the bonds holding dead skin cells together — initiating even, controlled shedding without disrupting the barrier.
Enhances hydration within the stratum corneum
Supports moisture retention in the outer skin layer throughout the exfoliation process.
Supports mild enzymatic desquamation
Works with the skin's own natural shedding enzymes for a gentler, more comfortable exfoliation.
Promotes smoother texture and increased luminosity
Surface refinement that reveals brighter, more even-looking skin.
Minimal inflammatory signaling
The skin responds without overreacting — controlled activity, calm results.
A clinical renewal peel delivering deeper, progressive exfoliation.
The progression peel. For clients who've established tolerance and are ready for deeper correction. This is where you start to see meaningful improvement in texture, tone, and skin function — without crossing into aggressive territory.
Step 2 in the Neuro Signal™ system:
Extends the signaling window for deeper, progressive renewal. Corneodesmosome breakdown becomes more sustained, allowing for deeper exfoliation and improved texture.
WHAT IT DOES
Sustains continuous corneodesmosome dissolution
Keeps breaking down the bonds that hold dead skin cells together — so shedding happens consistently and evenly, not in patches.
Increases the depth of epidermal desquamation
Exfoliation reaches deeper into the outer skin layer for more thorough renewal — beyond what a surface-level peel can achieve.
Elevates keratinocyte renewal signaling
Tells the skin cells responsible for new skin production to accelerate — so fresher, healthier skin rises to the surface faster.
Initiates a controlled cytokine response
Triggers the skin's healing messengers in a measured way — enough to activate repair, not enough to cause unnecessary inflammation.
Improves texture, tone, and cellular turnover
Skin feels smoother, looks more even, and renews itself more efficiently over time.
An advanced resurfacing peel delivering high workload and extended renewal signaling.
Advanced correction for skin that's ready for it. Higher concentration, same philosophy — working with the skin's biology at the nerve level, not against it.
Step 3 in the Neuro Signal™ system:
Delivers advanced resurfacing through sustained biological communication. The higher acid workload creates a larger reservoir, sustaining cellular communication and accelerating visible change. Texture refines. Tone evens. Skin function improves.
WHAT IT DOES
Drives continuous corneodesmosome breakdown across the stratum corneum
Aggressive but controlled cellular bond dissolution — sustained and thorough across the full outer skin layer.
Accelerates epidermal turnover with a sustained acid reservoir effect
Higher acid concentration creates a reservoir at the skin's surface, continuing to supply active molecules over time — extending the treatment's signaling window beyond the application itself.
Amplifies cytokine signaling and cellular response
A stronger activation of the skin's repair and renewal messengers — producing more significant and faster visible change.
Increases depth and intensity of desquamation
Deeper, more intensive exfoliation for clients whose skin is conditioned and ready for advanced correction.
Requires controlled application and post-treatment support
This concentration demands professional expertise — precise application and proper post-treatment care are essential to results.
More details pros will want to know
All three concentrations are built on the same neurogenic base formula. The ingredients don't change — the intensity does. What increases with each strength is the lactic acid concentration and the pH, which together determine how deep the signal goes and how much cellular work gets done. This is a progressive system, not three separate products. Same intelligent formula. Three levels of depth.
Lactic Acid (AHA) The active exfoliant.
A gentle alpha hydroxy acid that loosens bonds between dead skin cells and initiates cellular renewal signaling. At higher concentrations, it creates an acid reservoir that extends biological communication beyond the treatment itself.
Palmitoyl Tripeptide-8
A neuropeptide that communicates directly with the skin's nerve response. Helps regulate inflammatory signals and guide the healing process — so the skin's reaction works for the outcome, not against it.
Acetyl Tetrapeptide-40
A peptide that supports vascular regulation and skin comfort during treatment — contributing to the modulation of the skin-nervous response that defines this system.
Agastache Mexicana Flower/Leaf/Stem Extract
A calming botanical adaptogen that helps stabilize the skin's response to stress — reducing unnecessary irritation and supporting barrier recovery throughout the treatment.
Dextran
Supports hydration and barrier function keeping the skin stable and comfortable while the deeper neurogenic work happens.
Tetrahexyldecyl Ascorbate
A stable, oil-soluble form of Vitamin C. Supports brightening and antioxidant protection during and after the treatment.
DL-Panthenol (Vitamin B5)
Supports skin healing, hydration, and comfort — helping the barrier recover efficiently post-treatment.
Aloe Vera Leaf Extract
Calms and hydrates — reducing the sensation of heat and supporting post-treatment comfort.
Full ingredients list: Purified Water, Aloe Vera Leaf Extract, Lactic Acid, Glycerin, Sodium Hydroxide, Xanthan Gum, Dextran, Palmitoyl Tripeptide-8, Agastache Mexicana Flower/Leaf/Stem Extract, Tetrahexyldecyl Ascorbate, DL-Panthenol, Butylene Glycol, Hydroxyethylcellulose, Propanediol, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Acetyl Tetrapeptide-40.
The protocol is the same across all three concentrations. What changes is the depth of response.
PRE-TREATMENT CONDITIONING (2 Weeks Prior)Recommend a 2-week skin conditioning routine before your client's first peel. This builds barrier resilience, reduces sensitivity triggers, and ensures the skin fully tolerates the active ingredients for maximum results.
DAY OF
Readiness Check Before First Peel
- No active irritation
- No open lesions or flare-ups
- Barrier feels hydrated and strong
Cleanse & Prep
- Cleanse: Stratum Sync Foam Cleanser
- Degrease: Peel Activator Solution
- Apply: Your chosen Neuroscience Lactic Peel (30%, 35%, or 45%)
Baseline Application
- 1 pass: forehead → temples → cheeks → nose → chin
- Wait 2-3 minutes. Assess sensation (sting ≤3/10)
- Watch the skin, not the clock
Optional 2nd Pass (only if barrier is performing)
- Avoid over-inflamed areas (active rosacea papules)
- Move on at: slight pinking, tingling — but not prickling or heat intensification
FINISH THE TREATMENT
Buffer:Hydrating Cleanser and/or Cooling Globes — gently massage any hot spots, remove with tepid water
Mask:CopperTide Masque — 3-7 minutes, then remove.
Cool Down:Mist Trauma Spray & Apply Barrier Post Op Mask
Hydrate:PDRN Cellular Currency with Even Tone
Protect:Apply your favorite ClearChoice SPF 45 32 oz here or SPF 30 8 oz here.
BOOSTERS — Advanced Application
Estheticians can elevate outcomes and increase service value by adding targeted boosters:
- Stack 1: Melanin Suppressant — applied under Step 2, Lactic Acid 30% Peel
- Stack 2: Stem Cells — over Enhancer
- Stack 3: Pure A — over the peel
SKIN TEMPERATURE NOTE
- Cooler skin = less sensation
- Warmer skin = increased product kinetic activity
- Consider climate-conscious treatments accordingly
- Cleanse: Sensi Cream Cleanser
Serum: Oceuticals Collection B5 Healing Complex
Day Cream: Oceuticals Collection Opticream
Night Cream: Oceuticals Collection Night Shield
Mask: Oceuticals Collection Coppertide Masque
- Cleanse: Mandelic CleanserSerum: LumiLacti-CDay Cream: Reconstructive Brightening CreamNight Cream: Even Tone
- Cleanse: Micro-Dose Cleanser
Serum: Agevity Heavy Serum – Coming soon; Sodium Hyaluronate Day Cream
Day Cream: Age-Defying Moisture
Night Cream: Anti-Wrinkle Retinox
- Cleanse: Lipid Bond CleanserSerum: Vita-C B5 ComplexDay Cream: Moisture ClearNight Cream: Resist Rewind Night PM LotionExfoliation: Clear Balance Pads
Frequently asked questions
What is the Neuro Signal™ Peeling System? The Neuro Signal™ system is ClearChoice's approach to chemical peeling — one that incorporates neurogenic ingredients alongside lactic acid to guide how the skin responds to the treatment. Rather than relying purely on acid intensity to drive results, it uses peptides and botanicals to modulate the skin's nerve response, reduce unnecessary inflammation, and direct energy toward repair and renewal.
What is Agevity™ and what does it do? Agevity™ is ClearChoice's term for the state of skin that is actively regenerating, repairing, and performing at its biological best — rather than simply reacting to stress. It's the result of treatments that guide the skin rather than force it. When the inflammatory cascade is moderated and the nervous system stays calm, the skin's energy is redirected from defense to regeneration. That's Agevity™-driven skin performance.
What does pH mean in this system and why does it matter? pH determines the intensity of the acid's activity on the skin. Lower pH = stronger signal. The 30% peel at pH 3 delivers a gentle, controlled signal. The 35% at pH 2.5 goes deeper. The 45% at pH 2 delivers the most advanced workload. Importantly, in this system pH controls intensity — but neurogenic ingredients control the outcome. That's what makes this system different from simply using a lower pH peel.
What makes this different from a basic lactic acid peel? A basic lactic acid peel exfoliates and hydrates. This system does that — and also modulates the skin-nervous response beneath the barrier. By incorporating neuropeptides and calming botanicals, it guides how the skin reacts to the treatment, reduces unnecessary inflammation, and extends the biological signaling window beyond the treatment itself. The result is more than exfoliation — it's guided skin performance.
What are the boosters and what do they do? Boosters are targeted serums that can be layered with the peel to address specific skin concerns — pigmentation, cellular renewal, or advanced correction. They amplify the peel's results without adding downtime, and give estheticians a way to customize the treatment and increase service value.
How often can my client receive this treatment? This depends on the concentration and the client's skin. Because the system is designed to be progressive and non-inflammatory, treatments can generally be scheduled more consistently than aggressive peels. Consult with your us for specific frequency recommendations based on your client's skin condition and goals.
What is corneodesmosome dissolution and why does it matter? Corneodesmosomes are the protein bonds that hold dead skin cells together in the outer layer of skin. Dissolving them is how chemical exfoliation works — it signals the skin to shed those cells and reveal fresher skin beneath. The 35% sustains this process continuously. The 45% drives it across the full stratum corneum for deeper, more thorough renewal.
What is epidermal desquamation? Desquamation is the skin's natural shedding process — the orderly turnover of dead skin cells. Chemical peels accelerate and deepen this process. The Neuro Signal™ system supports desquamation without triggering the inflammatory overreaction that can come with more aggressive peels.
What is keratinocyte renewal signaling? Keratinocytes are the primary cells of the outer skin layer. When they receive the right signals, they accelerate their renewal cycle — producing fresher, healthier skin faster. The 35% peel elevates these signals, helping the skin renew itself more efficiently without overstimulation.
What is a cytokine response and is it safe? Cytokines are chemical messengers the skin uses to coordinate healing and repair. A controlled cytokine response is a normal, healthy part of the skin's renewal process. The key word is controlled — the Neuro Signal™ system is designed to activate repair signaling without triggering an excessive inflammatory cascade. Inflammation is moderated, not amplified.
What are neuropeptides and what do they do in a peel? Neuropeptides are small protein fragments that communicate between nerve cells and skin cells. In this system, Palmitoyl Tripeptide-8 and Acetyl Tetrapeptide-40 help regulate the skin's nerve response during treatment — moderating the inflammatory cascade, supporting vascular calm, and guiding the skin toward repair rather than defense.
What are adaptogens and why are they in a peel? Adaptogens help biological systems manage stress more effectively. Agastache Mexicana — the botanical adaptogen in this formula — helps stabilize the skin's response to the controlled stress of the peel. Rather than overreacting, the skin holds steady through the treatment and recovers more efficiently afterward.
What is the acid reservoir effect? At higher concentrations — particularly the 45% — acid molecules diffuse inward and bind to proteins in the skin, creating a reservoir that continues to supply active molecules over time. This extends the biological signaling window beyond the treatment itself, meaning the skin continues to respond and renew even after the peel has been removed.
How do I know my client is ready for each concentration? Start with the 30% for any new client, sensitized skin, or compromised barrier. Move to the 35% once the client has established tolerance and the barrier is performing consistently. The 45% is for clients who have progressed through the system and are ready for advanced correction. Never jump concentrations — the progressive system is the protocol.
What should my client avoid before the treatment? No active irritation, open lesions, or flare-ups. The barrier should feel hydrated and strong. Avoid retinoids, aggressive exfoliation, or anything that compromises the barrier in the 2 weeks prior. A pre-treatment conditioning routine is recommended before the first peel.
What should my client do after the treatment? Follow the recommended home care protocol — Mandelic Cleanser, Micro-Dose Cleanser, Night Shield, Even Tone, Lumi LactiC, Reconstructive Brightening Creme, and Agevity Heavy Serum. Avoid sun exposure and always apply SPF.
What results can my client expect and when? Because this is a progressive system, results build over time rather than appearing dramatically after one treatment. Clients typically notice improved texture and luminosity early. Deeper improvements in tone, barrier function, and skin resilience develop over a series of treatments.
Is there downtime? No. Zero downtime is a defining feature of this system. Because neurogenic ingredients moderate the inflammatory response throughout the treatment, the skin recovers comfortably — without the redness, peeling, or social downtime associated with more aggressive peels.
Can this be used on sensitive skin? The 30% is specifically designed as the entry point for sensitized skin and compromised barriers. The pre-treatment conditioning protocol and readiness check ensure the skin is prepared before any peel is applied. The neurogenic formulation moderates the inflammatory response across all three concentrations, making this system significantly more comfort-forward than traditional lactic peels.
California Skincare Supply
Why we carry it
We're a three-generation, female-owned esthetician team — and we only stock what we'd actually use in the treatment room and recommend without hesitation.
The ClearChoice Neuroscience Lactic Peel System is one of those products we got genuinely excited about. Not because it's new — but because it's right. It matches where professional skincare is heading: results-driven, biology-informed, and wellness-conscious. A system that respects the skin enough to work with it.
We're proud to be Dermastart's exclusive distributor — and proud to bring this to your treatment room.
Kelli & Jullea Anderson
California Skincare Supply · Est. 1990
California Skincare Supply has no minimum order requirement Orders are usually processed within 2-3 business days. Freight charges are non-refundable.
Makeup returns: We do not accept returns of any makeup that's been opened. We do accept returns of makeup if the packaging has been damaged.
Return's must be expressly authorized by CSS and are for store credit only. Returns and requests for order corrections must be made within 7 days of the receipt of the order. No returns allowed on 1/2 used product.
No unused product returns or exchanges accepted beyond 30 days of purchase date.
No returns on equipment, handhelds or skincare tools.
Returns must not be priced, marked or damaged in anyway, and received in resaleable condition.
California Residents: A California Sellers Permit from the California State Board of Equalization should be provided for all orders shipped within (or purchased in) the state of California. This tax number will exempt retail products from being taxed. Products sold for professional use are always taxable in the state of California; if a Sellers Permit is not provided the entire order will be taxable.
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